What to do if you receive the "Microsoft Outlook Autodiscover" pop-up as shown below. This pop-up does not indicate that your system is compromised but instead Exchange (Outlook) is needing information to configure your client correctly.
If the URL contains: "https://autodiscover.tccd.edu/autodiscover/autodiscover.xml" then It is safe to check Don't ask me about this website again, then click Allow